Quinupristin-Dalfopristin Is Active against Toxoplasma gondii

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Quinupristin-dalfopristin is active against Toxoplasma gondii.

Synercid and each of its components (quinupristin and dalfopristin) were examined for their activities against Toxoplasma gondii. In vitro, intracellular replication of tachyzoites was inhibited by synercid and each of its two components. The 50% inhibitory concentrations of synercid, quinupristin, and dalfopristin were 1.6, 2.7, and 6.3 microg/ml, respectively. Thus, synercid was markedly more...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1999

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.43.8.2043